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The BNF recently (2019) changed its guidance for the frequency of injections of hydroxocobalamin: Every 2 months in patients who have neurological symptoms Every 2 or 3 months when there are no neurological symptoms

Conservative dosing also reduces risk of excessive energy deficit and the metabolic stress markers (low T3, menstrual irregularity) that emerge when both compounds are pushed to upper dose ranges simultaneously.

Methylcobalamin is the active, naturally occurring form your body can use immediately supporting methylation, energy, and nerve health